Key Points

  • Depression is a common consequence of SCI.
  • Depression post SCI can interfere with function and adaptation.
  • Cognitive behavioural interventions provided in a group setting appear helpful in reducing post-SCI depression and related difficulties.
  • The benefits of drug treatment for post-SCI depression are largely extrapolated from studies in non-SCI populations.
  • Programs to encourage regular exercise, reduce stress, and improve or maintain health appear to have benefits in reducing reports of depressive symptoms in persons with SCI.