• Anti-inflammatory medications given early post-SCI reduces development of heterotopic ossification.
  • Warfarin may inhibit the development of heterotopic ossification post-SCI.
  • Etidronate can halt the progression of heterotopic ossification.
  • Pamidronate halts secondary progression of HO post surgical excision.
  • Pulse low intensity electromagnetic field therapy is effective in preventing HO post SCI.
  • Radiotherapy can reduce the progression of heterotopic ossification.
  • Surgical resection of HO can improve hip range of motion.
  • Surgical resection and pamidronate treatment halts secondary HO progression.