Frankel & Mathias 1980;  UK
Downs & Black = 11
Prospective Controlled Trial
N=5

Population: 5 patients with complete SCI; age range: 25-37 years; level of injury: C5-T4, 5-108 months post-injury
Treatment: trans-rectal electrical ejaculation with and without intravenous administration of Prostaglandin E2.
Outcome Measures: heart rate, blood pressure, electrocardiogram.

1. Resting BP decreased and resting HR increased with Prostaglandin E2.
2. BP decreased during electrical stimulation, which enabled tolerance of more intense stimulation and successful ejaculation in 2 patients.