Autonomic Dysreflexia Table 17 Sildanefil (Viagra)

Author Year; Country
Score
Research Design
Sample Size

Methods

Outcome

Sheel et al. 2005; Canada
PEDro = 5
RCT
N=13

Population: 13 males, 8 subjects with cervical and 5 with thoracic injuries
Treatment: oral dose of sildenafil citrate (25-100 mg) or no medication during penile vibratory stimulation
Outcomes Measures: ECG, blood pressure

  1. Sildenafil decreased base BP in cervical SCI.
  2. Men with cervical SCI had more pronounced AD during penile vibrostimulation than men with thoracic injuries.
  3. Administration of sildenafil had no effect on HR or BP during AD triggered by penile vibratory stimulation in men with SCI.