Nutrition Table 5 Nutrient Supplementation and Lipid Profile Post SCI

Submitted by admin on Fri, 05/21/2010 - 09:11

Author Year
Country
Score
Research Design
Sample Size

Methods

Outcomes

Javierre et al. 2005
Spain
Downs & Black score=15
Pre-post
N=19

Population: SCI: Severity of injury: AIS: A –D; Time since injury >12 yrs.
Treatment: Subjects were administered daily doses of DHA (1.5g) and EPA (.75g) in the form of gelatin pearls, 6 per day to be taken with their principal meals.
Outcome Measures: Plasma DHA, EPA, cholesterol (total, HDL, LDL, VLDL), triglycerides, and glucose measured following an overnight fast at baseline, 3 and 6 months.
  1. Plasma EPA and DHA increased significantly (p<0.05) in response to the intake of the supplement. 
  2. An increase was noted when comparing the levels before and after EPA was administered in the 3 month period and again at the 6-month period (p<0.05).  The same could be seen when looking at the percentages of DHA between the 3 time periods.  A significant increase was noted (p<0.05).
  3. No differences in cholesterol (total, HDL, LDL, VLDL), triglycerides, or glucose were observed.

Note: AIS=ASIA Impairment Scale; DHA=docosahexaenoic acid; EPA=eicosapentaenoic acide; HDL=High Density Lipoprotein; LDL=Low Density Lipoprotein; VLDL=Very Low Density Lipoprotein