Nussbaum et al. 1994
Canada
PEDro=6
RCT
N=16

Population: Age = 15-61 yrs
Treatment: Subjects were assigned into one of three groups: control group received “standard” wound care consisting of twice daily cleansing with Hygeol (1:20) and Jelonet dressing, and avoidance of pressure on existing ulcers; Laser group received standard wound care plus laser treatment 3x weekly; Ultrasound/Utraviolet C (US/UVC) group received standard wound care with US and UVC treatments alternating over a 5 day period.
Outcome Measures: Healing rate, ulcer size.

1. Healing rate was not equal under all treatment conditions.
2. Paired comparisons showed the significant difference was between US/UVC and laser treatment with US/UVC showing greater effect on wound healing.
3. Mean percentage of change per week in ulcer size from day 0 to complete healing for control (32.4%), US/UVC (53.5%), and laser (23.7%)
4. Several subjects showed deterioration over the study.  Ulcers increased in size; (laser = 3, 62-167% change; control  = 1, 58% change; US/UVC = 1, 1% change). All ulcers healed by end of study with last ulcer healed in laser group by week 20 as opposed to US/UVC group at week 6.